The Challenge of Anticoagulation: Getting Research Into Practice

Anticoagulation for VTE – Lessons From Clinical Trials

Activity Details
  • Credit Amounts:
    • CME: 0.50
    • Other: 0.50
  • Cost: Free
  • Release: May 3, 2017
  • Expires: May 2, 2020
  • Estimated Time to Complete:
    30 Minutes
  • System Requirements:
  • Average User Rating:
    ( Ratings)

Faculty

Ajay K.  Kakkar Ajay K. Kakkar, BSc, MBBS, PhD, FRCS
Professor of Surgery
University College London
Chairman of University College London Partners Academic Health Science Partnership
Director of the Thrombosis Research Institute
London, United Kingdom

Needs Statement

Selection and duration of appropriate therapy for VTE can be improved in clinical practice. Physicians remain reluctant to prescribe anticoagulant (AC) prophylaxis in a large proportion of the population at risk for thromboembolic stroke.
Risk factors for bleeding in patients receiving thromboprophylaxis must be recognized by the treating physician. The management of VTE frequently carries significant clinical challenges.

Target Audience

Health care professionals who are faced with challenges of anticoagulation treatment including the management of patients with VTE and/or patients with atrial fibrillation. These include practicing cardiologists, hematologists/oncologists, and geriatricians as well as specialists in Emergency Medicine, Internal Medicine, and all other subspecialist clinicians interested in anticoagulant therapy.

Objectives

Upon completion of this educational activity, participants will be able to:

  • Distinguish the potential risks and benefits of non-VKA oral anticoagulants (NOACs) compared with the vitamin K antagonist, warfarin
  • Describe the optimal approach for the management of high-risk sub-groups (frail, renal impairment, prior VTE, high clot burden) basedon current evidence
  • Relate how to design an appropriate therapeutic regimen for the prevention of VTE recurrence basedon current evidence
  • Integrate the new features of the AT10 guidelines from American College of Chest Physicians on Antithrombotic Therapy for VTE Disease into every day practice

Accreditation

CME
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Kentucky College of Medicine, and Thrombosis Research Institute. The University of Kentucky College of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

The University of Kentucky College of Medicine designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

The University of Kentucky College of Medicine presents this activity for educational purposes only. Participants are expected to utilize their own expertise and judgment while engaged in the practice of medicine. The content of the presentations is provided solely by presenters who have been selected for presentations because of recognized expertise in their field.

Other
UK Healthcare CECentral certifies this activity for 0.50 hours of participation.

Faculty Disclosure

Christopher B. Granger, MD, (Planner) has relevant financial relationships with commercial interests as follows:
Armetheon - Principal Investigator, Research Support, Salary Support
AstraZeneca - Principal Investigator, Consultant & Other Services, Research Support, Consulting Fee
Bayer - Principal Investigator, Consultant & Other Services, Salary Support, Consulting Fee
Boehringer Ingelheim - Principal Investigator, Consultant & Other Services, Research Support, Salary Support, Consulting Fee
Bristol Myers Squibb - Principal Investigator, Consultant & Other Services, Research Support, Salary Support, Consulting Fee
Eli Lilly - Consultant & Other Services, Consulting Fee
Daiichi Sankyo - Principal Investigator, Consultant & Other Services, Research Support, Salary Support, Consulting Fee
FDA - Principal Investigator, Research Support
Gilead - Consultant & Other Services, Consulting Fee
Glaxo SmithKline - Principal Investigator, Consultant & Other Services, Research Support, Salary Support, Consulting Fee
Hoffman-La Roche - Consultant & Other Services, Consulting Fee
Janssen Pharmaceuticals - Principal Investigator, Research Support
The Medicines Company - Principal Investigator, Consultant & Other Services, Research Support, Salary Support, Consulting Fee
Medtronic Foundation - Principal Investigator, Research Support, Salary Support

Lord Ajay Kakkar, BSc, MBBS, PhD, FRCS, (Planner and Speaker) has relevant financial relationships with commercial interests as follows:
Aspen Pharma - Consultant, Expert Testimony, Principal Investigator, Consultant Fee, Research Support, Honoraria
Bayer Healthcare - Consultant, Expert Testimony, Principal Investigator, Consultant Fee, Research Support, Honoraria
Boehringer Ingelheim Pharma - Consultant, Expert Testimony, Principal Investigator, Consultant Fee, Research Support, Honoraria
Daiichi Sankyo Europe - Consultant, Expert Testimony, Principal Investigator, Consultant Fee, Research Support, Honoraria
Sanofi SA - Consultant, Expert Testimony, Principal Investigator, Consultant Fee, Research Support, Honoraria

No other planners or reviewers have any relevant financial relationships to disclose.

The material presented in this course represents information obtained from the scientific literature as well as the clinical experiences of the speakers. In some cases, the presentations might include discussion of investigational agents and/or off-label indications for various agents used in clinical practice. Speakers will inform the audience when they are discussing investigational and/or off-label uses.

Content review confirmed that the content was developed in a fair, balanced manner free from commercial bias. Disclosure of a relationship is not intended to suggest or condone commercial bias in any presentation, but it is made to provide participants with information that might be of potential importance to their evaluation of a presentation.

Acknowledgement

This activity is jointly provided by the University of Kentucky and Thrombosis Research Institute.

Supported by an unrestricted educational grant from Bayer.

FRONTLINE 2 Survey

The Fundamental Research in Oncology and Thrombosis (FRONTLINE 2) Survey is designed to evaluate how clinicians perceive the risk of venous thromboembolism in cancer patients and to provide insight into current strategies for thromboprophylaxis and management. It has been developed with the guidance of an international advisory board of experts in this field. This survey is coordinated by the Thrombosis Research Institute, London. It has been developed with the guidance of an international advisory board of experts in this field. All replies will be treated in the strictest confidence. The survey is split into 5 Sections (A-E) and will take approximately 20 - 30 minutes to complete.

To complete the survey, visit http://frontline2.tri-london.ac.uk/